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| The two main hormones are thyroxine and triiodythyronine. The thyroid gland also produces calcitonin, which stimulates bone cells to add calcium to bone, as well as regulating calcium metabolism. Endocrine diseases There are three broad groups of endocrine disorders: Endocrine gland hyposecretion - when the gland is not producing enough. Endocrine gland hypersecretion - when the gland is overactive and produces too much. Tumors of endocrine glands - these may be malignant (cancerous) or benign (non-cancerous). Below are some examples of what may occur if a gland secretes too much or too little of its hormones: Adrenal Gland hypersecretion may lead to over-nervousness, sweating, raised blood pressure, and Cushing's disease.
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Adrenal Gland hyposecretion may lead to Addison's disease, Mineralocorticoid deficiency, and diabetes. Pancreas hypersecretion may lead to hyperinsulinism, too much insulin and not enough glucose gets to the brain. Parathyroid Gland hypersecretion may lead to brittle bones that fracture easily, as well as stones in the urinary system. Parathyroid Gland hyposecretion may lead to muscle tetany, caused by low levels of calcium in plasma. Thyroid Gland hypersecretion may lead to Graves disease, accelerated metabolism, sweating, arrhythmia (irregular heart beat), weight loss, and nervousness. Thyroid Gland hyposecretion may lead to tiredness, weight gain, depression, abnormal bone development, mental retardation, and stunted growth. Pituitary Gland hypersecretion may lead to gigantism (excessive growth). Pituitary Gland hyposecretion may lead to slow bone growth (dwarfism).
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